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uBio  Web  Results 1 - 10 of about 20059 Broader Terms:    clinical     environmental samples  More Specific:    uncultured     uncultured bacterium     uncultured clinical     uncultured clinical bacterium      External Resources: 1.  MMP11 promotes the proliferation and progression of breast cancer through stabilizing Smad2 protein. Zhuang Y, Li X, Zhan P, Pi G, Wen G Oncology reports, 2021 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0 2.  Situational context influences the degree of hostile attributions made by individuals with schizophrenia or autism spectrum disorder. Zajenkowska A, Rogoza R, Sasson NJ, Harvey PD, Penn DL, Pinkham AE The British journal of clinical psychology Br J Clin Psychol Situational context influences the degree of hostile attributions made by individuals with schizophrenia or autism spectrum disorder. 10.1111/bjc.12283 Previous work has demonstrated that the tendency to make hostile attributions is not a stable trait but varies across different social situations. Therefore, we sought to investigate whether hostile attributions within clinical samples are better understood as a persistent characteristic or one that varies across contexts. The current analyses investigated patterns of attributions among people diagnosed with schizophrenia (SCZ, n = 271) or autism spectrum disorder (ASD, n = 100) and non-clinical control participants (NCC, n = 233) in an existing data set. Results showed that specific relational features in vignettes portraying different social encounters influence the way people make attributions and that variability across contexts is present in both non-clinical and clinical populations. Like non-clinical participants, participants diagnosed with ASD ascribed the greatest hostility to a scene involving an authority figure. In contrast, SCZ participants reported the greatest hostility in response to a scene involving a friend. These findings suggest that salient environmental factors should be considered when assessing social cognitive skills and biases. Hostile attributions should be perceived as situational constructs rather than stable and persistent characteristics. Hostile attributions were most prevalent among persons diagnosed with schizophrenia; however, on average, all participants showed greater hostility for situations involving an authority figure, an acquaintance, or a friend relative to those involving a co-worker or stranger. Psychotherapists and clinicians working with people diagnosed with schizophrenia or autism spectrum disorder could work on identifying situation triggers, which may prompt hostile attributions. Psycho-educational and psychotherapeutic interventions can be altered based on individual triggers of hostile attributions, and attempts can be made to lessen these attributions. Paranoia appears to be linked to hostile attributions regardless of the specific clinical diagnosis and should be considered in the therapeutic process. © 2021 The British Psychological Society. Zajenkowska Anna A https://orcid.org/0000-0002-9413-1428 Insitute of Psychology, Maria Grzegorzewska University, Warsaw, Poland. Rogoza Rados?aw R Insitute of Psychology, Cardinal Wyszy?ski University, Warsaw, Poland. Sasson Noah J NJ School of Behavioral and Brain Sciences, The University of Texas at Dallas, Richardson, Texas, USA. Harvey Philip D PD Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Florida, USA. Research Service, Miami VA Healthcare System, Miami, Florida, USA. Penn David L DL Department of Psychology and Neuroscience, University of North Carolina-Chapel Hill, Chapel Hill, North Carolina, USA. School of Behavioural and Health Sciences, Australian Catholic University, Melbourne, Victoria, Australia. Pinkham Amy E AE School of Behavioral and Brain Sciences, The University of Texas at Dallas, Richardson, Texas, USA. Department of Psychiatry, University of Texas Southwestern Medical School, Dallas, Texas, USA. eng Journal Article 2021 03 01 England Br J Clin Psychol 8105533 0144-6657 IM ASD hostile attributions measurement invariance schizophrenia 2020 07 15 2021 01 20 2021 3 2 6 24 2021 3 3 6 0 2021 3 3 6 0 aheadofprint 33650108 10.1111/bjc.12283 Microbiologyopen Novel multiplex TaqMan assay for differentiation of the four major pathogenic Brachyspira species in swine. e1169 10.1002/mbo3.1169 A novel TaqMan 5-plex real-time PCR using a combination of locked nucleic acid-modified (LNA)- and minor groove binding (MGB)-conjugated DNA probes was developed for identification and differentiation between the four main pathogenic Brachyspira species in swine. B. hyodysenteriae, B. pilosicoli, and B. suanatina are identified using three hydrolysis probes targeting cpn60, while B. hampsonii is recognized by another nox specific probe. The assay also includes an exogenous internal control simultaneously verifying the PCR competency of the DNA samples. Validation of the novel assay was performed using DNA samples from 18 Brachyspira reference strains and 477 clinical samples obtained from porcine rectal swabs by comparing them with different PCR-based methods targeting nox, 16S rDNA, and 23S rDNA. The specificity of the assay was 100% without cross-reactivity or detection of different pathogens. Depending on the Brachyspira species, the limit of detection was between 10 and 20 genome equivalents with a cut-off threshold cycle (Ct) value of 37. The developed highly sensitive and specific 5-plex real-time PCR assay is easy to implement in routine veterinary diagnostic laboratories and enables rapid differentiation between the main four pathogenic Brachyspira species recognized in pigs using a single-tube approach. © 2021 The Authors. MicrobiologyOpen published by John Wiley & Sons Ltd. Scherrer Simone S https://orcid.org/0000-0001-9548-8798 Department of Veterinary Bacteriology, Institute for Food Safety and Hygiene, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland. Stephan Roger R Department of Veterinary Bacteriology, Institute for Food Safety and Hygiene, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland. eng Journal Article England Microbiologyopen 101588314 2045-8827 IM B. hampsonii B. hyodysenteriae B. pilosicoli B. suanatina Brachyspira species differentiation LNA- and MGB-probes TaqMan 5-plex qPCR 2020 11 04 2021 01 15 2021 01 19 2021 3 2 8 42 2021 3 3 6 0 2021 3 3 6 0 ppublish 33650802 10.1002/mbo3.1169