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Synonyms:
   Conger conger (Sea eel) 
   Ophidium pellucidum 

Broader Terms:
   Ophidium 
 
 
Latest Articles on Ophidium pellucidum from uBioRSS
Branchial NH - Frontiers in Zoology
A Vertical Wall Dominated by Acesta excavata and Neopycnodonte zibrowii, Pa... - PubMed: nov sp species


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1.  Primary intraventricular tumors - Imaging characteristics, post-treatment changes and relapses.LinkIT
Chong AW, McAdory LE, Low DCY, Lim EJ, Leong NWL, Ho CL
Clinical imaging, 2022
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0

2.  Rhomboencephalosynapsis: Review of the Literature.LinkIT
Fouda MA, Kim TY, Cohen AR
World neurosurgery, 2021
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0

3.  Structural MRI profiles and tau correlates of atrophy in autopsy-confirmed CTE.19310.1186/s13195-021-00928-yChronic traumatic encephalopathy (CTE), a neurodegenerative tauopathy, cannot currently be diagnosed during life. Atrophy patterns on magnetic resonance imaging could be an effective in vivo biomarker of CTE, but have not been characterized. Mechanisms of neurodegeneration in CTE are unknown. Here, we characterized macrostructural magnetic resonance imaging features of brain donors with autopsy-confirmed CTE. The association between hyperphosphorylated tau (p-tau) and atrophy on magnetic resonance imaging was examined.Magnetic resonance imaging scans were obtained by medical record requests for 55 deceased symptomatic men with autopsy-confirmed CTE and 31 men (n = 11 deceased) with normal cognition at the time of the scan, all >60 years Three neuroradiologists visually rated regional atrophy and microvascular disease (0 [none]-4 [severe]), microbleeds, and cavum septum pellucidum presence. Neuropathologists rated tau severity and atrophy at autopsy using semi-quantitative scales.Compared to unimpaired males, donors with CTE (45/55=stage III/IV) had greater atrophy of the orbital-frontal (mean diff.=1.29), dorsolateral frontal (mean diff.=1.31), superior frontal (mean diff.=1.05), anterior temporal (mean diff.=1.57), and medial temporal lobes (mean diff.=1.60), and larger lateral (mean diff.=1.72) and third (mean diff.=0.80) ventricles, controlling for age at scan (ps<0.05). There were no effects for posterior atrophy or microvascular disease. Donors with CTE had increased odds of a cavum septum pellucidum (OR = 6.7, p < 0.05). Among donors with CTE, greater tau severity across 14 regions corresponded to greater atrophy on magnetic resonance imaging (beta = 0.68, p < 0.01).These findings support frontal-temporal atrophy as a magnetic resonance imaging finding of CTE and show p-tau accumulation is associated with atrophy in CTE.© 2021. The Author(s).AloscoMichael LMLhttp://orcid.org/0000-0002-8113-8428Boston University Alzheimer's Disease Research Center and CTE Center, Department of Neurology, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.MianAsim ZAZDepartment of Radiology, Boston University School of Medicine, Boston, USA.BuchKarenKDepartment of Radiology, Massachusetts General Hospital, Boston, USA.FarrisChad WCWDepartment of Radiology, Boston University School of Medicine, Boston, USA.Department of Radiology, Massachusetts General Hospital, Boston, USA.UretskyMadelineMBoston University Alzheimer's Disease Research Center and CTE Center, Department of Neurology, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.TripodisYorghosYDepartment of Biostatistics, Boston University School of Public Health, Boston, USA.BaucomZacharyZDepartment of Biostatistics, Boston University School of Public Health, Boston, USA.MartinBrettBBiostatistics and Epidemiology Data Analytics Center, Boston University School of Public Health, Boston, USA.PalmisanoJosephJBiostatistics and Epidemiology Data Analytics Center, Boston University School of Public Health, Boston, USA.PuzoChristianCBoston University Alzheimer's Disease Research Center and CTE Center, Department of Neurology, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.AngTing Fang AlvinTFAFramingham Heart Study, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.JoshiPrajaktaPFramingham Heart Study, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.GoldsteinLee ELEBoston University Alzheimer's Disease Research Center and CTE Center, Department of Neurology, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.Department of Radiology, Boston University School of Medicine, Boston, USA.Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, USA.Department of Psychiatry, Boston University School of Medicine, Boston, USA.Departments of Biomedical, Electrical & Computer Engineering, Boston University College of Engineering, Boston, USA.AuRhodaRBoston University Alzheimer's Disease Research Center and CTE Center, Department of Neurology, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.Framingham Heart Study, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, USA.Department of Epidemiology, Boston University School of Public Health, Boston, USA.KatzDouglas IDIBoston University Alzheimer's Disease Research Center and CTE Center, Department of Neurology, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.Braintree Rehabilitation Hospital, Braintree, MA, USA.DwyerBrigidBBoston University Alzheimer's Disease Research Center and CTE Center, Department of Neurology, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.Braintree Rehabilitation Hospital, Braintree, MA, USA.DaneshvarDaniel HDHBoston University Alzheimer's Disease Research Center and CTE Center, Department of Neurology, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.NowinskiChristopherCConcussion Legacy Foundation, Boston, MA, USA.CantuRobert CRCBoston University Alzheimer's Disease Research Center and CTE Center, Department of Neurology, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.Concussion Legacy Foundation, Boston, MA, USA.Department of Neurosurgery, Boston University School of Medicine, Boston, USA.Department of Neurosurgery, Emerson Hospital, Concord, USA.KowallNeil WNWBoston University Alzheimer's Disease Research Center and CTE Center, Department of Neurology, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, USA.US Department of Veteran Affairs, VA Boston Healthcare System, Boston, USA.HuberBertrand RussellBRBoston University Alzheimer's Disease Research Center and CTE Center, Department of Neurology, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.US Department of Veteran Affairs, VA Boston Healthcare System, Boston, USA.National Center for PTSD, VA Boston Healthcare, Boston, USA.AlvarezVictor EVEBoston University Alzheimer's Disease Research Center and CTE Center, Department of Neurology, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.US Department of Veteran Affairs, VA Boston Healthcare System, Boston, USA.Department of Veterans Affairs Medical Center, Bedford, MA, USA.SternRobert ARABoston University Alzheimer's Disease Research Center and CTE Center, Department of Neurology, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, USA.Department of Neurosurgery, Boston University School of Medicine, Boston, USA.SteinThor DTDBoston University Alzheimer's Disease Research Center and CTE Center, Department of Neurology, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.Framingham Heart Study, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, USA.US Department of Veteran Affairs, VA Boston Healthcare System, Boston, USA.Department of Veterans Affairs Medical Center, Bedford, MA, USA.KillianyRonald JRJBoston University Alzheimer's Disease Research Center and CTE Center, Department of Neurology, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, USA.Center for Biomedical Imaging, Boston University School of Medicine, Boston, USA.McKeeAnn CACBoston University Alzheimer's Disease Research Center and CTE Center, Department of Neurology, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.Framingham Heart Study, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, USA.US Department of Veteran Affairs, VA Boston Healthcare System, Boston, USA.Department of Veterans Affairs Medical Center, Bedford, MA, USA.MezJesseJBoston University Alzheimer's Disease Research Center and CTE Center, Department of Neurology, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA. jessemez@bu.edu.Framingham Heart Study, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA. jessemez@bu.edu.engAG054156AGNIA NIH HHSUnited StatesU54NS115266NSNINDS NIH HHSUnited StatesP30 AG072978AGNIA NIH HHSUnited StatesU54 NS115266NSNINDS NIH HHSUnited StatesI01-CX001038U.S. Department of Veterans AffairsAG016495AGNIA NIH HHSUnited StatesAG008122AGNIA NIH HHSUnited StatesAG062109AGNIA NIH HHSUnited StatesAG049810AGNIA NIH HHSUnited StatesK23AG046377AGNIA NIH HHSUnited StatesRF1AG054156AGNIA NIH HHSUnited StatesU01NS086659NSNINDS NIH HHSUnited StatesP30AG072978AGNIA NIH HHSUnited StatesK23NS102399NSNINDS NIH HHSUnited StatesJournal Article20211207EnglandAlzheimers Res Ther101511643IMAtrophyChronic traumatic encephalopathyMagnetic resonance imagingNeurodegenerationTau20210913202110312021128543202112960202112960epublish3487622910.1186/s13195-021-00928-y10.1186/s13195-021-00928-yPMC8653514Alzheimers Res Ther. 2015 Oct 12;7(1):6226455775Dement Geriatr Cogn Disord. 2011;31(5):371-821625137Acta Neuropathol. 2016 Jan;131(1):75-8626667418Eur Radiol. 2011 Dec;21(12):2618-2521805370Dement Geriatr Cogn Disord. 2007;23(5):334-4217374952Acta Neuropathol. 2014 Dec;128(6):755-6625348064Neuroimage Clin. 2019;24:10202531670152JAMA Neurol. 2019 Nov 1;76(11):1298-130831380975Brain. 2013 Jan;136(Pt 1):43-6423208308Dev Med Child Neurol. 2014 Sep;56(9):839-4524750109Am J Epidemiol. 1979 Sep;110(3):281-90474565J Neurol Neurosurg Psychiatry. 1992 Oct;55(10):967-721431963Nature. 2018 Sep;561(7721):137-14030158706J Neuropathol Exp Neurol. 2009 Jul;68(7):709-3519535999Alzheimers Dement. 2018 Sep;14(9):1159-117030049650Neuroimage Clin. 2017 Sep 25;17:452-46429159058Acta Neuropathol. 2015 Dec;130(6):877-8926518018AJR Am J Roentgenol. 1987 Aug;149(2):351-63496763J Neurotrauma. 2016 Jan 1;33(1):157-6125970145J Neuropathol Exp Neurol. 2020 Aug 1;79(8):921-92432688381Brain Imaging Behav. 2019 Jun;13(3):725-73429779184Int Psychogeriatr. 2013 Jan;25(1):111-922809815JAMA Neurol. 2015 Jul;72(7):773-8025985094N Engl J Med. 2019 May 2;380(18):1716-172530969506Neuroradiology. 2009 Aug;51(8):491-50319308367JAMA Neurol. 2013 Mar 1;70(3):326-3523303193J Neuropathol Exp Neurol. 2021 Feb 22;80(3):210-21933611507Arch Neurol. 2006 Nov;63(11):1627-3117101833J Neuropathol Exp Neurol. 1995 Jan;54(1):42-567815079Appl Neuropsychol Adult. 2012;19(2):108-1523373577Alzheimers Dement (Amst). 2017 Nov 06;10:56-6529201991Ann Neurol. 2020 Jan;87(1):116-13131589352J Neuropsychiatry Clin Neurosci. 2000 Summer;12(3):344-910956567J Neurotrauma. 2016 Feb 15;33(4):346-5326414478Sci Transl Med. 2020 Jan 1;12(524):31894103Am J Epidemiol. 2007 Jun 1;165(11):1328-3517372189Brain. 2016 May;139(Pt 5):1551-6726962052JAMA. 2017 Jul 25;318(4):360-37028742910Alzheimers Dement. 2021 Oct;17(10):1709-172433826224Neurobiol Dis. 2015 Feb;74:58-6525447235Am J Public Health Nations Health. 1951 Mar;41(3):279-8114819398Acta Neuropathol. 2017 Mar;133(3):337-35228205009Nature. 2020 Apr;580(7802):283-28732050258N Engl J Med. 2016 Feb 11;374(6):523-3226863354Acta Neuropathol. 2008 May;115(5):509-3217985145Nature. 2019 Apr;568(7752):420-42330894745Brain. 2016 Apr;139(Pt 4):1211-2526936938AJNR Am J Neuroradiol. 2017 Jul;38(7):1303-131028473342Acta Neuropathol. 2020 Oct;140(4):495-51232778942Neurology. 2020 Jan 21;94(3):e232-e24031871218J Alzheimers Dis. 2018;66(2):601-61130320588JAMA Neurol. 2020 Jan 1;77(1):35-423149837126937548NBK349073University of Washington, SeattleSeattle (WA)GeneReviews®199319932022AdamMargaret PMPArdingerHolly HHHPagonRoberta ARAWallaceStephanie ESEBeanLora JHLJHGrippKaren WKWMirzaaGhayda MGMAmemiyaAnneAInternetFGFR1-Related Hartsfield SyndromeLinkIT
Alosco ML, Mian AZ, Buch K, Farris CW, Uretsky M, Tripodis Y, Baucom Z, Martin B, Palmisano J, Puzo C, Ang TFA, Joshi P, Goldstein LE, Au R, Katz DI, Dwyer B, Daneshvar DH, Nowinski C, Cantu RC, Kowall NW, Huber BR, Alvarez VE, Stern RA, Stein TD, Killiany RJ, McKee AC, Mez J, , Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Mirzaa GM, Amemiya A, , Dhamija R, Babovic-Vuksanovic D
Alzheimer's research & therapy, 2021Dec07Alzheimer's research & therapyAlzheimers Res TherStructural MRI profiles and tau correlates of atrophy in autopsy-confirmed CTE.19310.1186/s13195-021-00928-yChronic traumatic encephalopathy (CTE), a neurodegenerative tauopathy, cannot currently be diagnosed during life. Atrophy patterns on magnetic resonance imaging could be an effective in vivo biomarker of CTE, but have not been characterized. Mechanisms of neurodegeneration in CTE are unknown. Here, we characterized macrostructural magnetic resonance imaging features of brain donors with autopsy-confirmed CTE. The association between hyperphosphorylated tau (p-tau) and atrophy on magnetic resonance imaging was examined.Magnetic resonance imaging scans were obtained by medical record requests for 55 deceased symptomatic men with autopsy-confirmed CTE and 31 men (n = 11 deceased) with normal cognition at the time of the scan, all >60 years Three neuroradiologists visually rated regional atrophy and microvascular disease (0 [none]-4 [severe]), microbleeds, and cavum septum pellucidum presence. Neuropathologists rated tau severity and atrophy at autopsy using semi-quantitative scales.Compared to unimpaired males, donors with CTE (45/55=stage III/IV) had greater atrophy of the orbital-frontal (mean diff.=1.29), dorsolateral frontal (mean diff.=1.31), superior frontal (mean diff.=1.05), anterior temporal (mean diff.=1.57), and medial temporal lobes (mean diff.=1.60), and larger lateral (mean diff.=1.72) and third (mean diff.=0.80) ventricles, controlling for age at scan (ps<0.05). There were no effects for posterior atrophy or microvascular disease. Donors with CTE had increased odds of a cavum septum pellucidum (OR = 6.7, p < 0.05). Among donors with CTE, greater tau severity across 14 regions corresponded to greater atrophy on magnetic resonance imaging (beta = 0.68, p < 0.01).These findings support frontal-temporal atrophy as a magnetic resonance imaging finding of CTE and show p-tau accumulation is associated with atrophy in CTE.© 2021. The Author(s).AloscoMichael LMLhttp://orcid.org/0000-0002-8113-8428Boston University Alzheimer's Disease Research Center and CTE Center, Department of Neurology, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.MianAsim ZAZDepartment of Radiology, Boston University School of Medicine, Boston, USA.BuchKarenKDepartment of Radiology, Massachusetts General Hospital, Boston, USA.FarrisChad WCWDepartment of Radiology, Boston University School of Medicine, Boston, USA.Department of Radiology, Massachusetts General Hospital, Boston, USA.UretskyMadelineMBoston University Alzheimer's Disease Research Center and CTE Center, Department of Neurology, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.TripodisYorghosYDepartment of Biostatistics, Boston University School of Public Health, Boston, USA.BaucomZacharyZDepartment of Biostatistics, Boston University School of Public Health, Boston, USA.MartinBrettBBiostatistics and Epidemiology Data Analytics Center, Boston University School of Public Health, Boston, USA.PalmisanoJosephJBiostatistics and Epidemiology Data Analytics Center, Boston University School of Public Health, Boston, USA.PuzoChristianCBoston University Alzheimer's Disease Research Center and CTE Center, Department of Neurology, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.AngTing Fang AlvinTFAFramingham Heart Study, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.JoshiPrajaktaPFramingham Heart Study, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.GoldsteinLee ELEBoston University Alzheimer's Disease Research Center and CTE Center, Department of Neurology, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.Department of Radiology, Boston University School of Medicine, Boston, USA.Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, USA.Department of Psychiatry, Boston University School of Medicine, Boston, USA.Departments of Biomedical, Electrical & Computer Engineering, Boston University College of Engineering, Boston, USA.AuRhodaRBoston University Alzheimer's Disease Research Center and CTE Center, Department of Neurology, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.Framingham Heart Study, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, USA.Department of Epidemiology, Boston University School of Public Health, Boston, USA.KatzDouglas IDIBoston University Alzheimer's Disease Research Center and CTE Center, Department of Neurology, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.Braintree Rehabilitation Hospital, Braintree, MA, USA.DwyerBrigidBBoston University Alzheimer's Disease Research Center and CTE Center, Department of Neurology, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.Braintree Rehabilitation Hospital, Braintree, MA, USA.DaneshvarDaniel HDHBoston University Alzheimer's Disease Research Center and CTE Center, Department of Neurology, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.NowinskiChristopherCConcussion Legacy Foundation, Boston, MA, USA.CantuRobert CRCBoston University Alzheimer's Disease Research Center and CTE Center, Department of Neurology, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.Concussion Legacy Foundation, Boston, MA, USA.Department of Neurosurgery, Boston University School of Medicine, Boston, USA.Department of Neurosurgery, Emerson Hospital, Concord, USA.KowallNeil WNWBoston University Alzheimer's Disease Research Center and CTE Center, Department of Neurology, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, USA.US Department of Veteran Affairs, VA Boston Healthcare System, Boston, USA.HuberBertrand RussellBRBoston University Alzheimer's Disease Research Center and CTE Center, Department of Neurology, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.US Department of Veteran Affairs, VA Boston Healthcare System, Boston, USA.National Center for PTSD, VA Boston Healthcare, Boston, USA.AlvarezVictor EVEBoston University Alzheimer's Disease Research Center and CTE Center, Department of Neurology, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.US Department of Veteran Affairs, VA Boston Healthcare System, Boston, USA.Department of Veterans Affairs Medical Center, Bedford, MA, USA.SternRobert ARABoston University Alzheimer's Disease Research Center and CTE Center, Department of Neurology, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, USA.Department of Neurosurgery, Boston University School of Medicine, Boston, USA.SteinThor DTDBoston University Alzheimer's Disease Research Center and CTE Center, Department of Neurology, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.Framingham Heart Study, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, USA.US Department of Veteran Affairs, VA Boston Healthcare System, Boston, USA.Department of Veterans Affairs Medical Center, Bedford, MA, USA.KillianyRonald JRJBoston University Alzheimer's Disease Research Center and CTE Center, Department of Neurology, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, USA.Center for Biomedical Imaging, Boston University School of Medicine, Boston, USA.McKeeAnn CACBoston University Alzheimer's Disease Research Center and CTE Center, Department of Neurology, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.Framingham Heart Study, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA.Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, USA.US Department of Veteran Affairs, VA Boston Healthcare System, Boston, USA.Department of Veterans Affairs Medical Center, Bedford, MA, USA.MezJesseJBoston University Alzheimer's Disease Research Center and CTE Center, Department of Neurology, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA. jessemez@bu.edu.Framingham Heart Study, Boston University School of Medicine, 72 E Concord Street, Suite B7800, Boston, MA, 02118, USA. jessemez@bu.edu.engAG054156AGNIA NIH HHSUnited StatesU54NS115266NSNINDS NIH HHSUnited StatesP30 AG072978AGNIA NIH HHSUnited StatesU54 NS115266NSNINDS NIH HHSUnited StatesI01-CX001038U.S. Department of Veterans AffairsAG016495AGNIA NIH HHSUnited StatesAG008122AGNIA NIH HHSUnited StatesAG062109AGNIA NIH HHSUnited StatesAG049810AGNIA NIH HHSUnited StatesK23AG046377AGNIA NIH HHSUnited StatesRF1AG054156AGNIA NIH HHSUnited StatesU01NS086659NSNINDS NIH HHSUnited StatesP30AG072978AGNIA NIH HHSUnited StatesK23NS102399NSNINDS NIH HHSUnited StatesJournal Article20211207EnglandAlzheimers Res Ther101511643IMAtrophyChronic traumatic encephalopathyMagnetic resonance imagingNeurodegenerationTau20210913202110312021128543202112960202112960epublish3487622910.1186/s13195-021-00928-y10.1186/s13195-021-00928-yPMC8653514Alzheimers Res Ther. 2015 Oct 12;7(1):6226455775Dement Geriatr Cogn Disord. 2011;31(5):371-821625137Acta Neuropathol. 2016 Jan;131(1):75-8626667418Eur Radiol. 2011 Dec;21(12):2618-2521805370Dement Geriatr Cogn Disord. 2007;23(5):334-4217374952Acta Neuropathol. 2014 Dec;128(6):755-6625348064Neuroimage Clin. 2019;24:10202531670152JAMA Neurol. 2019 Nov 1;76(11):1298-130831380975Brain. 2013 Jan;136(Pt 1):43-6423208308Dev Med Child Neurol. 2014 Sep;56(9):839-4524750109Am J Epidemiol. 1979 Sep;110(3):281-90474565J Neurol Neurosurg Psychiatry. 1992 Oct;55(10):967-721431963Nature. 2018 Sep;561(7721):137-14030158706J Neuropathol Exp Neurol. 2009 Jul;68(7):709-3519535999Alzheimers Dement. 2018 Sep;14(9):1159-117030049650Neuroimage Clin. 2017 Sep 25;17:452-46429159058Acta Neuropathol. 2015 Dec;130(6):877-8926518018AJR Am J Roentgenol. 1987 Aug;149(2):351-63496763J Neurotrauma. 2016 Jan 1;33(1):157-6125970145J Neuropathol Exp Neurol. 2020 Aug 1;79(8):921-92432688381Brain Imaging Behav. 2019 Jun;13(3):725-73429779184Int Psychogeriatr. 2013 Jan;25(1):111-922809815JAMA Neurol. 2015 Jul;72(7):773-8025985094N Engl J Med. 2019 May 2;380(18):1716-172530969506Neuroradiology. 2009 Aug;51(8):491-50319308367JAMA Neurol. 2013 Mar 1;70(3):326-3523303193J Neuropathol Exp Neurol. 2021 Feb 22;80(3):210-21933611507Arch Neurol. 2006 Nov;63(11):1627-3117101833J Neuropathol Exp Neurol. 1995 Jan;54(1):42-567815079Appl Neuropsychol Adult. 2012;19(2):108-1523373577Alzheimers Dement (Amst). 2017 Nov 06;10:56-6529201991Ann Neurol. 2020 Jan;87(1):116-13131589352J Neuropsychiatry Clin Neurosci. 2000 Summer;12(3):344-910956567J Neurotrauma. 2016 Feb 15;33(4):346-5326414478Sci Transl Med. 2020 Jan 1;12(524):31894103Am J Epidemiol. 2007 Jun 1;165(11):1328-3517372189Brain. 2016 May;139(Pt 5):1551-6726962052JAMA. 2017 Jul 25;318(4):360-37028742910Alzheimers Dement. 2021 Oct;17(10):1709-172433826224Neurobiol Dis. 2015 Feb;74:58-6525447235Am J Public Health Nations Health. 1951 Mar;41(3):279-8114819398Acta Neuropathol. 2017 Mar;133(3):337-35228205009Nature. 2020 Apr;580(7802):283-28732050258N Engl J Med. 2016 Feb 11;374(6):523-3226863354Acta Neuropathol. 2008 May;115(5):509-3217985145Nature. 2019 Apr;568(7752):420-42330894745Brain. 2016 Apr;139(Pt 4):1211-2526936938AJNR Am J Neuroradiol. 2017 Jul;38(7):1303-131028473342Acta Neuropathol. 2020 Oct;140(4):495-51232778942Neurology. 2020 Jan 21;94(3):e232-e24031871218J Alzheimers Dis. 2018;66(2):601-61130320588JAMA Neurol. 2020 Jan 1;77(1):35-423149837126937548NBK349073University of Washington, SeattleSeattle (WA)GeneReviews®1993
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0

4.  Septo-Optic Dysplasia Diagnosed in a Newborn Infant with Normoglycemia: The Importance of Thorough Physical Examination.LinkIT
Palorath A, Kharode I
Case reports in pediatrics, 2021
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0

5.  What Are the Double Lines of the Fetal Cavum Septi Pellucidi on Ultrasound?LinkIT
Green S, Pretorius DH, Crouch A, Anton T, Jacobs M, Ho Y, Hevner R, Lamale-Smith L
Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in MedicineJ Ultrasound MedWhat Are the Double Lines of the Fetal Cavum Septi Pellucidi on Ultrasound?10.1002/jum.15867To demonstrate the significance of the double line appearance of the septi pellucidi laminae (SPL) on fetal ultrasound.A total of 522 uncomplicated singleton pregnancies (15 to 39?weeks' gestational age) with fetal ultrasounds were enrolled. The presence of a single versus double line SP as well as measurement of the cavum septi pellucidi (CSP) was determined retrospectively. Ultrasound settings from the CSP images were recorded. Thickness of the SPL was measured in 20 ultrasound and 14 MRI cases; histology was reviewed from one neonate. Maternal BMI and gestational age were also recorded.The presence of double line SPL is a normal sonographic finding, seen in 47% (188/403) of normal fetuses. Thickness of the SPL in 10 cases with double line averaged 1.4?mm and in 10 cases with single line averaged 0.8?mm; MRI measurements were within 0.1?mm of the corresponding ultrasound measurements. Double line cavum was more often seen with mid-dynamic contrast range settings (5, 6) rather than high range settings (7-10) (P value <.05). The double line was only visualized on ultrasound when the angle of insonation was at or near perpendicular to the laminae; it was never visualized on coronal ultrasound imaging or MRI imaging.A double line septum pellucidum lamina is a normal finding seen in almost 50% of uncomplicated singleton pregnancies. It may be attributed to borders of cell layers within each lamina that form separate specular reflections on both sides; this can be accentuated by ultrasound settings and beam angulation.© 2021 American Institute of Ultrasound in Medicine.GreenShannonSDepartment of Radiology, University of California, San Diego, San Diego, California, USA.PretoriusDolores HDHhttps://orcid.org/0000-0001-8258-1635Department of Radiology, University of California, San Diego, San Diego, California, USA.Maternal-Fetal Care and Genetics, University of California, San Diego, La Jolla, California, USA.CrouchAmandaAMaternal-Fetal Care and Genetics, University of California, San Diego, La Jolla, California, USA.Department of Reproductive Medicine, University of California, San Diego, La Jolla, California, USA.AntonTracyTMaternal-Fetal Care and Genetics, University of California, San Diego, La Jolla, California, USA.Department of Reproductive Medicine, University of California, San Diego, La Jolla, California, USA.JacobsMarniMMaternal-Fetal Care and Genetics, University of California, San Diego, La Jolla, California, USA.HoYoonaYDepartment of Radiology, Scripps Health, La Jolla, California, USA.HevnerRobertRDepartment of Pathology, University of California, San Diego, San Diego, California, USA.Lamale-SmithLeahLhttps://orcid.org/0000-0003-0572-3980Maternal-Fetal Care and Genetics, University of California, San Diego, La Jolla, California, USA.Department of Reproductive Medicine, University of California, San Diego, La Jolla, California, USA.engJournal Article20211109EnglandJ Ultrasound Med82115470278-4297IMcavum septi pellucidifetal cavumfetal cavum septum pellucidumfetal central nervous systemprenatal ultrasoundsepti pellucidi laminae202110062021071220211007202111992420211110602021111060aheadofprint3475146410.1002/jum.15867References, 2021</i></font><br><font color=#008000>http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0<br></font></span><br>6.  <a href=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0 class=title>Complications of neuroendoscopic septostomy.</a><a href=http://ubio.org/tools/linkit.php?map%5B%5D=all&link_type=2&url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0><img src=linkit.png border=0 title='LinkIT' alt='LinkIT'></a> <br><span class=j>Atchley TJ, Sowers B, Arynchyna AA, Rozzelle CJ, Rocque BG<br><font color=gray><i>Journal of neurosurgery. Pediatrics, 2021</i></font><br><font color=#008000>http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0<br></font></span><br>7.  <a href=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0 class=title>Teenage Neurologic Manifestation of a Complex Brain Malformation Consisting of Gray Matter Heterotopia, Schizencephaly and Absent Septum Pellucidum.</a><a href=http://ubio.org/tools/linkit.php?map%5B%5D=all&link_type=2&url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0><img src=linkit.png border=0 title='LinkIT' alt='LinkIT'></a> <br><span class=j>Hustings N, Lemmerling M<br><font color=gray><i>Journal of the Belgian Society of Radiology, 2021</i></font><br><font color=#008000>http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0<br></font></span><br>8.  <a href=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0 class=title>Novel disease-causing variants and phenotypic features of X-linked megalocornea.</a><a href=http://ubio.org/tools/linkit.php?map%5B%5D=all&link_type=2&url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0><img src=linkit.png border=0 title='LinkIT' alt='LinkIT'></a> <br><span class=j>Dudakova L, Tuft S, Cheong SS, Skalicka P, Jedlickova J, Fichtl M, Hlozanek M, Filous A, Vaneckova M, Vincent AL, Hardcastle AJ, Davidson AE, Liskova P<br><font color=gray><i>Acta ophthalmologicaActa OphthalmolNovel disease-causing variants and phenotypic features of X-linked megalocornea.10.1111/aos.15022The aim of the study was to describe the phenotype and molecular genetic causes of X-linked megalocornea (MGC1). We recruited four British, one New Zealand, one Vietnamese and four Czech families.All probands and three female carriers underwent ocular examination and Sanger sequencing of the CHRDL1 gene. Two of the probands also had magnetic resonance imaging (MRI) of the brain.We identified nine pathogenic or likely pathogenic and one variant of uncertain significance in CHRDL1, of which eight are novel. Three probands had ocular findings that have not previously been associated with MGC1, namely pigmentary glaucoma, unilateral posterior corneal vesicles, unilateral keratoconus and unilateral Fuchs heterochromic iridocyclitis. The corneal diameters of the three heterozygous carriers were normal, but two had abnormally thin corneas, and one of these was also diagnosed with unilateral keratoconus. Brain MRI identified arachnoid cysts in both probands, one also had a neuroepithelial cyst, while the second had a midsagittal neurodevelopmental abnormality (cavum septum pellucidum et vergae).The study expands the spectrum of pathogenic variants and the ocular and brain abnormalities that have been identified in individuals with MGC1. Reduced corneal thickness may represent a mild phenotypic feature in some heterozygous female carriers of CHRDL1 pathogenic variants.© 2021 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.DudakovaLubicaLhttps://orcid.org/0000-0003-4718-8955Research Unit for Rare Diseases, Department of Paediatrics and Inherited Metabolic Disorders, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic.TuftStephenShttps://orcid.org/0000-0001-8192-5192Moorfields Eye Hospital, London, UK.CheongSek-ShirSSUCL Institute of Ophthalmology, London, UK.SkalickaPavlinaPhttps://orcid.org/0000-0002-7403-3433Research Unit for Rare Diseases, Department of Paediatrics and Inherited Metabolic Disorders, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic.Department of Ophthalmology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic.JedlickovaJanaJResearch Unit for Rare Diseases, Department of Paediatrics and Inherited Metabolic Disorders, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic.FichtlMarekMDepartment of Ophthalmology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic.HlozanekMartinMDepartment of Ophthalmology, Second Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic.Ophthalmology Department, Third Faculty of Medicine, Charles University and Teaching Hospital Kralovske Vinohrady, Prague, Czech Republic.FilousAlesADepartment of Ophthalmology, Second Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic.VaneckovaManuelaMDepartment of Radiodiagnostics, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic.VincentAndrea LALDepartment of Ophthalmology, New Zealand National Eye Centre, University of Auckland, Auckland, New Zealand.HardcastleAlison JAJUCL Institute of Ophthalmology, London, UK.DavidsonAlice EAEUCL Institute of Ophthalmology, London, UK.LiskovaPetraPhttps://orcid.org/0000-0001-7834-8486Research Unit for Rare Diseases, Department of Paediatrics and Inherited Metabolic Disorders, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic.UCL Institute of Ophthalmology, London, UK.Department of Ophthalmology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic.engGACR 20-19278SGrantová Agentura C\?eské RepublikyUNCE/MED/007Univerzita Karlova v PrazePROGRES-Q26/LF1Univerzita Karlova v PrazeSVV 260367/2017Univerzita Karlova v PrazeJournal Article20211013EnglandActa Ophthalmol1014681021755-375XIMCHRDL1brain MRIheterozygous carrierskeratoconusmegalocorneaposterior corneal vesicles20210807202101312021083120211013173120211014602021101460aheadofprint3464443510.1111/aos.15022References, 2021</i></font><br><font color=#008000>http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0<br></font></span><br>9.  <a href=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0 class=title>Ganglioglioma Arising from the Septum Pellucidum.</a><a href=http://ubio.org/tools/linkit.php?map%5B%5D=all&link_type=2&url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0><img src=linkit.png border=0 title='LinkIT' alt='LinkIT'></a> <br><span class=j>Shrestha B, Gurung P, Dhakal S, Rajbhandari P, Basnet RB, Pant B<br><font color=gray><i>Journal of neurosciences in rural practice, 2021</i></font><br><font color=#008000>http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0<br></font></span><br><br><br><table cellspacing=0 cellpadding=0 align=center><tr valign=bottom><td align=center><img src=p.png border=0></td><td align=center><img src=o_red.png border=0></td><td align=center><img src=rtal.png border=0></td></tr><td align=center></td><td align=center>1</td><td align=center></td></tr></table></table></tr></table></td><script src="http://www.google-analytics.com/urchin.js" type="text/javascript"> </script> <script type="text/javascript"> _uacct = "UA-634822-1"; urchinTracker(); </script> </BODY> </HTML>