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1.  Isolation, screening and identification of key components having intense insect repellent activity against Plodia interpunctella from four different medicinal plant materials.LinkIT
Lee JS, Lee J, Choi I, Chang Y, Yoon CS, Han J
Journal of the science of food and agricultureJ Sci Food AgricIsolation, screening and identification of key components having intense insect repellent activity against Plodia interpunctella from four different medicinal plant materials.1105-111310.1002/jsfa.11447Global warming and the indiscriminate use of pesticides have increased the propagation of the stored-product insect pests, leading to enormous losses in the agriculture and food industries. The most used insect repellents are synthetic derivatives; however, these have an adverse effect on human health as well as on the environment. Therefore, we attempted to find materials with insect repellent activity in natural products. The present study aimed to identify the single chemical component with intense insect repellent activity in extracts from four different Oriental medicinal plant materials: (i) Anethum graveolens L. (dill) seeds; (ii) Artemisia capillaris Thunb. (capillary wormwood) leaves; (iii) smoked Prunus mume Siebold & Zucc. (mume) fruits; and (iv) Rhus javanica L. (galls).As a result of the bioassay-guided fractionation of each extract against the Plodia interpunctella, stored-product insect, the n-hexane fraction of dill seeds extract was confirmed as the optimal fraction between all of the fractions. In total, 32 chemical components were identified from the n-hexane fraction of dill seeds by gas chromatography-mass spectrometry analysis, and the two main components were dillapiole (47.51%) and carvone (26.76%). Of the two components, dillapiole was confirmed as the key component playing an essential role in insect repellent activity.Our study suggests that dillapiole has the potential to be used as a natural insect repellent for the control of P. interpunctella infestation in agricultural and food products during distribution and storage. © 2021 Society of Chemical Industry.© 2021 Society of Chemical Industry.LeeJung-SooJSDepartment of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, Republic of Korea.LeeJunhyukJDepartment of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, Republic of Korea.ChoiInyoungIDepartment of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, Republic of Korea.ChangYoonjeeYDepartment of Food and Nutrition, Kookmin University, Seoul, Republic of Korea.YoonChan SukCSAgency for Korea National Food Cluster (AnFC), Iksan, Republic of Korea.HanJaejoonJhttps://orcid.org/0000-0003-3199-889XDepartment of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, Republic of Korea.Department of Food Biosciences and Technology, College of Life Sciences and Biotechnology, Korea University, Seoul, Republic of Korea.engBiomedical Science and Food Safety, Korea University Food Safety Hall118048-03Korea Institute of Planning and Evaluation for Technology in Food, Agriculture, Forestry and FisheriesKorea University2020R1F1A1073901National Research Foundation of KoreaJournal Article20210810EnglandJ Sci Food Agric03763340022-51420Insect Repellents0Plant ExtractsIMAnethum graveolenschemistryAnimalsArtemisiachemistryBrucea javanicachemistryGas Chromatography-Mass SpectrometryInsect Repellentschemistryisolation & purificationpharmacologyLepidopteradrug effectsphysiologyPlant Extractschemistryisolation & purificationpharmacologyPlants, MedicinalchemistryPrunuschemistryPlodia interpunctellacarvonecolumn chromatographydillapiolemedicinal plantsolvent-solvent partitioning202104172020101220210729202173060202211360202172974ppublish3432288110.1002/jsfa.11447REFERENCES, 2022</i></font><br><font color=#008000>http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0<br></font></span><br>2.  <a href=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0 class=title>The Effects of Commercially Available <i>Syzygium aromaticum</i>, <i>Anethum graveolens</i>, <i>Lactobacillus acidophilus</i> LB, and Zinc as Alternatives Therapy in Experimental Mice Challenged with <i>Cryptosporidium parvum</i>.</a><a href=http://ubio.org/tools/linkit.php?map%5B%5D=all&link_type=2&url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0><img src=linkit.png border=0 title='LinkIT' alt='LinkIT'></a> <br><span class=j>Gaber M, Galal LAA, Farrag HMM, Badary DM, Alkhalil SS, Elossily N<br><font color=gray><i>Infection and drug resistance, 2022</i></font><br><font color=#008000>http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0<br></font></span><br>3.  <a href=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0 class=title>Dill Shows Potential for Herb-Drug Interactions via Up-Regulation of <i>CYP1A2</i>, <i>CYP2C19</i>, <i>SULT1A1</i>, <i>NAT2</i> and <i>ABCB1 </i>in Caco-2 Cells.</a><a href=http://ubio.org/tools/linkit.php?map%5B%5D=all&link_type=2&url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0><img src=linkit.png border=0 title='LinkIT' alt='LinkIT'></a> <br><span class=j>Udomsak W, Chatuphonprasert W, Jarukamjorn K<br><font color=gray><i>Pakistan journal of biological sciences : PJBS, 2022</i></font><br><font color=#008000>http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0<br></font></span><br>4.  <a href=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0 class=title>Anethum graveolens L. (Dill) Effect on Human Lipid Profile: An Updated Systematic Review.</a><a href=http://ubio.org/tools/linkit.php?map%5B%5D=all&link_type=2&url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0><img src=linkit.png border=0 title='LinkIT' alt='LinkIT'></a> <br><span class=j>Sadeghi M, Kabiri S, Amerizadeh A, Heshmat-Ghahdarijani K, Masoumi G, Teimouri-Jervekani Z, Amirpour A<br><font color=gray><i>Current problems in cardiology, 2021</i></font><br><font color=#008000>http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0<br></font></span><br>5.  <a href=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0 class=title>Bioactive Collagen Hydrolysate-Chitosan/Essential Oil Electrospun Nanofibers Designed for Medical Wound Dressings.</a><a href=http://ubio.org/tools/linkit.php?map%5B%5D=all&link_type=2&url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0><img src=linkit.png border=0 title='LinkIT' alt='LinkIT'></a> <br><span class=j>Râp? M, Gaidau C, Mititelu-Tartau L, Berechet MD, Berbecaru AC, Rosca I, Chiriac AP, Matei E, Predescu AM, Predescu C<br><font color=gray><i>Pharmaceutics, 2021</i></font><br><font color=#008000>http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0<br></font></span><br>6.  <a href=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0 class=title>Antispasmodic Potential of Medicinal Plants: A Comprehensive Review.</a><a href=http://ubio.org/tools/linkit.php?map%5B%5D=all&link_type=2&url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0><img src=linkit.png border=0 title='LinkIT' alt='LinkIT'></a> <br><span class=j>Rauf A, Akram M, Semwal P, Mujawah AAH, Muhammad N, Riaz Z, Munir N, Piotrovsky D, Vdovina I, Bouyahya A, Adetunji CO, Shariati MA, Almarhoon ZM, Mabkhot YN, Khan H<br><font color=gray><i>Oxidative medicine and cellular longevity, 2021</i></font><br><font color=#008000>http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0<br></font></span><br>7.  <a href=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0 class=title>Anti-Inflammation and Protective Effects of <i>Anethum graveolens</i> L. (Dill Seeds) on Esophageal Mucosa Damages in Reflux Esophagitis-Induced Rats.</a><a href=http://ubio.org/tools/linkit.php?map%5B%5D=all&link_type=2&url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0><img src=linkit.png border=0 title='LinkIT' alt='LinkIT'></a> <br><span class=j>Nam HH, Nan L, Choo BK<br><font color=gray><i>Foods (Basel, Switzerland), 2021</i></font><br><font color=#008000>http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0<br></font></span><br>8.  <a href=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0 class=title>Potential of Essential Oils from Anise, Dill and Fennel Seeds for the Gypsy Moth Control.</a><a href=http://ubio.org/tools/linkit.php?map%5B%5D=all&link_type=2&url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0><img src=linkit.png border=0 title='LinkIT' alt='LinkIT'></a> <br><span class=j>Kosti? I, Lazarevi? J, ?e?lija Jovanovi? D, Kosti? M, Markovi? T, Milanovi? S<br><font color=gray><i>Plants (Basel, Switzerland), 2021</i></font><br><font color=#008000>http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0<br></font></span><br>9.  <a href=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0 class=title>Favorable effects of <i>Anethum graveolens</i> on liver oxidative stress and cholesterol 7 alpha-hydroxylase levels in non-alcoholic fatty liver disease (NAFLD) rat models.</a><a href=http://ubio.org/tools/linkit.php?map%5B%5D=all&link_type=2&url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0><img src=linkit.png border=0 title='LinkIT' alt='LinkIT'></a> <br><span class=j>Abbasi E, Goodarzi MT, Tayebinia H, Saidijam M, Khodadadi I<br><font color=gray><i>Metabolism open, 2021</i></font><br><font color=#008000>http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0<br></font></span><br>10.  <a href=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0 class=title>Effect of satapushpa churnam with tila tailam in oligomenorrhea associated with polycystic ovarian syndrome.</a><a href=http://ubio.org/tools/linkit.php?map%5B%5D=all&link_type=2&url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0><img src=linkit.png border=0 title='LinkIT' alt='LinkIT'></a> <br><span class=j>Jacob J, Vijayakumar N, Olickal JJ<br><font color=gray><i>Journal of Ayurveda and integrative medicine, 2021</i></font><br><font color=#008000>http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0<br></font></span><br><br><br><table cellspacing=0 cellpadding=0 align=center><tr valign=bottom><td align=center><img src=p.png border=0></td><td align=center><img src=o_red.png border=0></td><td align=center><a href=http://ubio.org/portal/index.php?search=Anethum+panmorium&category=l&client=pubmed&startPage=2><img src=o_yellow.png border=0></a></td><td align=center><a href=http://ubio.org/portal/index.php?search=Anethum+panmorium&category=l&client=pubmed&startPage=3><img src=o_yellow.png border=0></a></td><td align=center><a href=http://ubio.org/portal/index.php?search=Anethum+panmorium&category=l&client=pubmed&startPage=4><img src=o_yellow.png border=0></a></td><td align=center><a href=http://ubio.org/portal/index.php?search=Anethum+panmorium&category=l&client=pubmed&startPage=5><img src=o_yellow.png border=0></a></td><td align=center><a href=http://ubio.org/portal/index.php?search=Anethum+panmorium&category=l&client=pubmed&startPage=6><img src=o_yellow.png border=0></a></td><td align=center><a href=http://ubio.org/portal/index.php?search=Anethum+panmorium&category=l&client=pubmed&startPage=7><img src=o_yellow.png border=0></a></td><td align=center><a href=http://ubio.org/portal/index.php?search=Anethum+panmorium&category=l&client=pubmed&startPage=8><img src=o_yellow.png border=0></a></td><td align=center><a href=http://ubio.org/portal/index.php?search=Anethum+panmorium&category=l&client=pubmed&startPage=9><img src=o_yellow.png border=0></a></td><td align=center><a href=http://ubio.org/portal/index.php?search=Anethum+panmorium&category=l&client=pubmed&startPage=10><img src=o_yellow.png border=0></a></td><td align=center><a href=http://ubio.org/portal/index.php?search=Anethum+panmorium&category=l&client=pubmed&startPage=2><img src=rtal.png border=0></a></td></tr><td align=center></td><td align=center>1</td><td align=center><a href=http://ubio.org/portal/index.php?search=Anethum+panmorium&category=l&client=pubmed&startPage=2>2</a></td><td align=center><a href=http://ubio.org/portal/index.php?search=Anethum+panmorium&category=l&client=pubmed&startPage=3>3</a></td><td align=center><a 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