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Synonyms:
   Swietenia macrophylla (Brazilian mahogany) 

Broader Terms:
   Sapindales 
   Swietenia (mahogany) 
 
 
Latest Articles on Swietenia macrophylla King from uBioRSS
Seed storage behaviour of 101 woody species from the tropical rainforest of... - Australian Journal of Botany
Discovery of potential anti-infectives against Staphylococcus aureus using ... - BMC Complementary and Alternative Medicine


External Resources:

Common Names: Honduras mahogany, Mara, Mogno, Bi, Brazilian mahogany, Mahogani grands feuilles, Large-leaved mahogany, Acajou, Caoba



1.  Weeds harbor Fusarium species that cause malformation disease of economically important trees in western Mexico.LinkIT
Montoya-Martínez AC, O'Donnell K, Busman M, Vaughan MM, McCormick SP, Santillán-Mendoza R, Pineda-Vaca D, Clapés-Garduño LE, Fernández-Pavía SP, Ploetz RC, Benítez-Malvido J, Montero-Castro JC, Rodriguez-Alvarado G
Plant disease, 2021
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0

2.  Anticancer potential of limonoids from Swietenia macrophylla: Genotoxic, antiproliferative and proapoptotic effects towards human colorectal cancer.LinkIT
Pinto LC, Mesquita FP, Barreto LH, Souza PFN, Ramos INF, Pinto AVU, Soares BM, da Silva MN, Burbano RMR, Montenegro RC
Life sciences, 2021
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0

3.  Diversity Patterns of Tropical Epigeal Beetle Assemblages Associated with Monoculture and Polyculture Plantations with Big-Leaf Mahogany.LinkIT
Quinto J, Martínez-Falcón AP, Murillo-Pacheco JI, Abdala-Roberts L, Parra-Tabla V
Neotropical entomology, 2021
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0

4.  Swietenine potentiates the antihyperglycemic and antioxidant activity of Metformin in Streptozotocin induced diabetic rats.LinkIT
Shiming Z, Mak KK, Balijepalli MK, Chakravarthi S, Pichika MR
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0

5.  Malformation Disease in Tabebuia rosea (Rosy Trumpet) Caused by Fusarium pseudocircinatum in Mexico.LinkIT
Montoya-Martínez AC, O'Donnell K, Busman M, Vaughan MM, McCormick SP, Santillán-Mendoza R, Pineda-Vaca D, Fernández-Pavía SP, Ploetz RC, Benítez-Malvido J, Montero-Castro JC, Rodriguez-Alvarado G
Plant disease, 2021
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0

6.  Limonoids isolated from fruits of Swietenia macrophylla king enhance glucose consumption in insulin-resistant HepG2 cells via activating PPAR?.LinkIT
Duan JY, Wang YJ, Chen W, Zhao YQ, Bai ZH, He LL, Zhang CP
Journal of food biochemistryJ Food BiochemLimonoids isolated from fruits of Swietenia macrophylla king enhance glucose consumption in insulin-resistant HepG2 cells via activating PPAR?.e1366810.1111/jfbc.13668The fruits of Swietenia macrophylla King have been processed commercially to a variety of health foods and healthcare products and exhibited antidiabetic, anti-inflammatory, antimutagenicity, antitumor activity, and so on. This study was aimed to examine the glucose consumption in human hepatoma HepG2 cells and the expression of PPAR? of limonoids isolated from the fruits of S. macrophylla. The phytochemical investigation of the fruits led to the isolation of ten limonoids which structures were elucidated by spectroscopic analysis as swietenine (1), khayasin T (2), 6-deoxyswietenine (3), 3-O-tigloylswietenolide (4), swietenolide (5), 3,6-O,O-diacetylswietenolide (6), 7-deacetoxy-7-oxogedunin (7), fissinolide (8), proceranolide (9), 7-deacetoxy-7?-hydroxygedunin (10), and compound 10 was isolated from this plant for the first time. The glucose consumption assay revealed that compounds 1, 2, 3, 5, and 9 could promote glucose consumption significantly in normal hyperglycemia-induced HepG2 cells, furthermore, compounds 1, 5, and 9 had a better effect on promoting glucose consumption in insulin-resistant HepG2 cells. In addition, compounds 1 and 5 could dramatically enhance the expression of PPAR? protein in insulin-resistant HepG2 cells according to the western blotting analysis result. PRACTICAL APPLICATIONS: Swietenia macrophylla King belongs to the family Meliaceae and the fruits have been exhibited a wide range of biological activities, such as antidiabetic, anti-inflammatory, antimutagenicity, antitumor activity, and so on. Phytochemical investigations of S. macrophylla have revealed that limonoids and triterpenoids were effective antidiabetic agents. However, the mechanism of these limonoids to antidiabetic activity is unclear. In this study, limonoids were isolated from the fruit of S. macrophylla and their effects on the glucose consumption of insulin-resistant HepG2 cells were studied. The results showed that compounds 1 and 5 could dramatically enhance the expression of PPAR? protein in insulin-resistant HepG2 cells, which will give aid to explore the mechanism of these limonoids in the treatment of type 2 diabetes. Therefore, this research might facilitate further research and development of S. macrophylla.© 2021 Wiley Periodicals LLC.DuanJing-YuJYJiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, School of Pharmacy, Xuzhou Medical University, Xuzhou, China.WangYong-JianYJJiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, School of Pharmacy, Xuzhou Medical University, Xuzhou, China.ChenWeiWJiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, School of Pharmacy, Xuzhou Medical University, Xuzhou, China.ZhaoYang-QiYQJiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, School of Pharmacy, Xuzhou Medical University, Xuzhou, China.BaiZhong-HuiZHJiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, School of Pharmacy, Xuzhou Medical University, Xuzhou, China.HeLiang-LiangLLJiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, School of Pharmacy, Xuzhou Medical University, Xuzhou, China.ZhangChun-PingCP0000-0002-2965-0117Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, School of Pharmacy, Xuzhou Medical University, Xuzhou, China.engJournal ArticleResearch Support, Non-U.S. Gov't20210219United StatesJ Food Biochem77060450145-88840Insulin0Limonins0PPAR gammaIY9XDZ35W2GlucoseIMDiabetes Mellitus, Type 2FruitGlucoseHep G2 CellsHumansInsulinLimoninspharmacologyMeliaceaePPAR gammageneticsHepG2 cellsPPAR?Swietenia macrophyllaglucose consumptionlimonoids202101302020110520210204202122060202179602021219840ppublish3360546110.1111/jfbc.13668REFERENCES, 2021</i></font><br><font color=#008000>http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0<br></font></span><br>7.  <a href=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0 class=title>Counteracting the Ramifications of UVB Irradiation and Photoaging with <i>Swietenia macrophylla</i> King Seed.</a><a href=http://ubio.org/tools/linkit.php?map%5B%5D=all&link_type=2&url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0><img src=linkit.png border=0 title='LinkIT' alt='LinkIT'></a> <br><span class=j>Mahendra CK, Abidin SAZ, Htar TT, Chuah LH, Khan SU, Ming LC, Tang SY, Pusparajah P, Goh BH<br><font color=gray><i>Molecules (Basel, Switzerland), 2021</i></font><br><font color=#008000>http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0<br></font></span><br>8.  <a href=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0 class=title>Shade tree species affect gas exchange and hydraulic conductivity of cacao cultivars in an agroforestry system.</a><a href=http://ubio.org/tools/linkit.php?map%5B%5D=all&link_type=2&url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0><img src=linkit.png border=0 title='LinkIT' alt='LinkIT'></a> <br><span class=j>Ávila-Lovera E, Blanco H, Móvil O, Santiago LS, Tezara W<br><font color=gray><i>Tree physiology, 2021</i></font><br><font color=#008000>http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0<br></font></span><br>9.  <a href=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0 class=title>Comparison of water-use characteristics of tropical tree saplings with implications for forest restoration.</a><a href=http://ubio.org/tools/linkit.php?map%5B%5D=all&link_type=2&url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0><img src=linkit.png border=0 title='LinkIT' alt='LinkIT'></a> <br><span class=j>Andriyas T, Leksungnoen N, Tor-Ngern P<br><font color=gray><i>Scientific reports, 2021</i></font><br><font color=#008000>http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0<br></font></span><br>10.  <a href=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0 class=title>Herb-induced autoimmune-like hepatitis associated with Xiang-tian-guo (Swietenia macrophylla seeds): A case report and literature review.</a><a href=http://ubio.org/tools/linkit.php?map%5B%5D=all&link_type=2&url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0><img src=linkit.png border=0 title='LinkIT' alt='LinkIT'></a> <br><span class=j>Shao YM, Zhang Y, Yin X, Qin TT, Jin QL, Wen XY<br><font color=gray><i>Medicine, 2021</i></font><br><font color=#008000>http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0<br></font></span><br><br><br><table cellspacing=0 cellpadding=0 align=center><tr valign=bottom><td align=center><img src=p.png border=0></td><td 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