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Synonyms:
   Citrus aurantium aurantium (sour orange) 

Broader Terms:
   Citrus (Citrus Fruits) 
   Citrus aurantium (Seville Orange) 
 
 


External Resources:

Common Names: sour orange



1.  Metabolites from the citrus extracts inhibit the activity of selected proteins in Indian Cobra (Naja naja) venom.LinkIT
R S, Gurunathan J
Journal of ethnopharmacology, 2020
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0

2.  The protective effect of hesperetin in osteoarthritis: an in vitro and in vivo study.LinkIT
Lin Z, Fu C, Yan Z, Wu Y, Zhan J, Lou Z, Liao X, Pan J
Food & function, 2020
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0

3.  Protein Extraction, Enrichment and MALDI MS and MS/MS Analysis from Bitter Orange Leaves (Citrusaurantium).LinkIT
Aiello D, Siciliano C, Mazzotti F, Di Donna L, Risoluti R, Napoli A
Molecules (Basel, Switzerland), 2020
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0

4.  Citrus aurantium L. bloom essential oil nanoemulsion: Synthesis, characterization, cytotoxicity, and its potential health impacts on mice.LinkIT
Navaei Shoorvarzi S, Shahraki F, Shafaei N, Karimi E, Oskoueian E
Journal of food biochemistry J. Food Biochem. Citrus aurantium L. bloom essential oil nanoemulsion: Synthesis, characterization, cytotoxicity, and its potential health impacts on mice. e13181 10.1111/jfbc.13181 This research was performed to synthesize the Citrus aurantium L. bloom essential oil nanoemulsion (CABE-NE) and investigate its cytotoxic and apoptotic impacts on human lung (A549 cells), and further, the effects of CABE-NE on mice health parameters was determined. The obtained results demonstrated that C. aurantium bloom contained 1.2 ± 0.16% of essential oil with linalyl acetate, limonene, and ?-terpineol as major compounds. The CABE-NE possessed particle size of 76.9 ± 6.11 nm, PDI of 0.19, and zeta potential of -43.5 mV. The CABE-NE indicated the cytotoxicity against A549 cells with the IC50 value of 152 µg/ml. The CABE-NE induced the overexpression of Cas-3 and triggered the apoptotic cells death. The mice gavaged daily with CABE-NE at the concentrations of 10 and 20 mg/kg body weight for 30 days did not show any remarkable histopathological alteration in the liver and kidney while exhibited enhancement in the jejunum morpho-structural architecture and hepatic antioxidant redox potential. PRACTICAL APPLICATIONS: According to the results, the produced CABE-NE drug delivery system could be considered as a promising alternative to prevent lung cancer progression and it provides a new way to enhance the therapeutic value of the plant phytochemicals. © 2020 Wiley Periodicals, Inc. Navaei Shoorvarzi Somayeh S Department of Biology, Mashhad Branch, Islamic Azad University, Mashhad, Iran. Shahraki Farzaneh F Department of Biology, Mashhad Branch, Islamic Azad University, Mashhad, Iran. Shafaei Negin N Department of Biology, Mashhad Branch, Islamic Azad University, Mashhad, Iran. Karimi Ehsan E https://orcid.org/0000-0002-5011-9611 Department of Biology, Mashhad Branch, Islamic Azad University, Mashhad, Iran. Oskoueian Ehsan E https://orcid.org/0000-0003-4821-190X Mashhad Branch, Agricultural Biotechnology Research Institute of Iran (ABRII), Agricultural Research, Education, and Extension Organization (AREEO), Mashhad, Iran. eng Journal Article 2020 03 15 United States J Food Biochem 7706045 0145-8884 IM drug delivery histopathology jejunum nanotechnology phytochemistry 2019 11 09 2020 01 13 2020 02 05 2020 3 17 6 0 2020 3 17 6 0 2020 3 17 6 0 aheadofprint 32173879 10.1111/jfbc.13181 REFERENCES, 2020</i></font><br><font color=#008000>http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0<br></font></span><br>5.  <a href=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0 class=title>Determination of the Volatile Profile of Lemon Peel Oils as Affected by Rootstock.</a><a href=http://ubio.org/tools/linkit.php?map%5B%5D=all&link_type=2&url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0><img src=linkit.png border=0 title='LinkIT' alt='LinkIT'></a> <br><span class=j>Aguilar-Hernández MG, Sánchez-Bravo P, Hernández F, Carbonell-Barrachina ÁA, Pastor-Pérez JJ, Legua P<br><font color=gray><i>Foods (Basel, Switzerland), 2020</i></font><br><font color=#008000>http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0<br></font></span><br>6.  <a href=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0 class=title>Selective pressurized extraction as single-step extraction and clean-up for the determination of organophosphate ester flame retardant in Citrus aurantium leaves by gas chromatography-tandem mass spectrometry.</a><a href=http://ubio.org/tools/linkit.php?map%5B%5D=all&link_type=2&url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0><img src=linkit.png border=0 title='LinkIT' alt='LinkIT'></a> <br><span class=j>Santos JL, Malvar JL, Abril C, Martín J, Aparicio I, Alonso E<br><font color=gray><i>Analytical and bioanalytical chemistry, 2020</i></font><br><font color=#008000>http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0<br></font></span><br>7.  <a href=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0 class=title>Naturally Occurring TPE-CA Maintains Gut Microbiota and Bile Acids Homeostasis <i>via</i> FXR Signaling Modulation of the Liver-Gut Axis.</a><a href=http://ubio.org/tools/linkit.php?map%5B%5D=all&link_type=2&url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0><img src=linkit.png border=0 title='LinkIT' alt='LinkIT'></a> <br><span class=j>Liu L, Liu Z, Li H, Cao Z, Li W, Song Z, Li X, Lu A, Lu C, Liu Y<br><font color=gray><i>Frontiers in pharmacology, 2020</i></font><br><font color=#008000>http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0<br></font></span><br>8.  <a href=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0 class=title>Systematic Detection and Identification of Bioactive Ingredients from <i>Citrus aurantium</i> L. var. <i>amara</i> Using HPLC-Q-TOF-MS Combined with a Screening Method.</a><a href=http://ubio.org/tools/linkit.php?map%5B%5D=all&link_type=2&url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0><img src=linkit.png border=0 title='LinkIT' alt='LinkIT'></a> <br><span class=j>Yu L, Chen M, Liu J, Huang X, He W, Qing Z, Zeng J<br><font color=gray><i>Molecules (Basel, Switzerland), 2020</i></font><br><font color=#008000>http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0<br></font></span><br>9.  <a href=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0 class=title>Hepatoprotective Effect of <i>Citrus aurantium L.</i> Against APAP-induced Liver Injury by Regulating Liver Lipid Metabolism and Apoptosis.</a><a href=http://ubio.org/tools/linkit.php?map%5B%5D=all&link_type=2&url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0><img src=linkit.png border=0 title='LinkIT' alt='LinkIT'></a> <br><span class=j>Shu Y, He D, Li W, Wang M, Zhao S, Liu L, Cao Z, Liu R, Huang Y, Li H, Yang X, Lu C, Liu Y<br><font color=gray><i>International journal of biological sciences, 2020</i></font><br><font color=#008000>http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0<br></font></span><br>10.  <a href=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0 class=title>Citrus Production Under Screen as a Strategy to Protect Grapefruit Trees From Huanglongbing Disease.</a><a href=http://ubio.org/tools/linkit.php?map%5B%5D=all&link_type=2&url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0><img src=linkit.png border=0 title='LinkIT' alt='LinkIT'></a> <br><span class=j>Ferrarezi RS, Qureshi JA, Wright AL, Ritenour MA, Macan NPF<br><font color=gray><i>Frontiers in plant science, 2019</i></font><br><font color=#008000>http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=0<br></font></span><br><br><br><table cellspacing=0 cellpadding=0 align=center><tr valign=bottom><td align=center><img src=p.png border=0></td><td align=center><img src=o_red.png border=0></td><td align=center><a 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